The results were presented by three special laboratories.
French and Swedish laboratories have confirmed Russian opposition leader Alexei Navalny was poisoned with a chemical nerve-agent of the Novichok group.
"We renew the call for Russia to explain what has happened. We are in close contact with our European partners on further steps," according to a statement posted on the German Government's website.
Germany has asked France and Sweden for an independent review of the German evidence based on Navalny's new samples, the report notes, adding that the results of the review confirm the German evidence.
"Regardless of the ongoing investigations by the OPCW, three laboratories have now independently provided evidence of a nerve agent from the Novichok group as the cause of Mr. Navalny's poisoning," the German Government said.