The monitoring group said 21 of those reportedly killed on Sunday morning were children, according to the BBC.
The village is in Deir al-Zour, one of the last provinces where Islamic State still holds territory.
Initially SOHR said 34 had been killed in strikes on residential buildings.
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Earlier Russia confirmed that six long-range bombers had carried out air strikes in the area, but said they had hit militants and their strongholds.
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UN-backed peace talks are expected to resume in Geneva next week, but several previous rounds of negotiations have failed.